The endoplasmic reticulum aminopeptidase ERAP1 regulates innate and adaptive immune responses by trimming peptides for presentation by major histocompatibility complex (MHC) class I molecules.Previously, we have shown that genetic or pharmacological inhibition of ERAP1 on murine and human tumor cell lines perturbs the engagement of NK cell inhibito

Partial oculosympathetic palsy followed by ischemic manifestations in brain or retina are the main symptoms of extracranial internal carotid artery (ICA) dissection.Unusually, cranial nerves may black mustang with pink stripes be affected.Isolated oculomotor nerve palsy is found only rarely.CASE: We present a 50-year-old nondiabetic man who experie

The leaf beetle Ambrostoma quadriimpressum (Coleoptera: Chrysomelidae) is a predominant forest pest that causes substantial damage to the lumber industry and city management.However, no effective and environmentally friendly chemical method has been discovered to control this pest.Until recently, the molecular basis of the olfactory system in A.qua

Due to their simplicity and operating mode, magnetic loops are one of the most used traffic sensors in Intelligent Transportation Systems (ITS).However, at this moment, their potential is not being fully exploited, as neither the speed nor the length of the vehicles can be surely ascertained with the use of a single magnetic loop.In this way, nowad

Abstract Background Spindle cell lipoma is a benign adipocytic tumour, commonly occuring in the masunaga tango subcutis of posterior neck, upper back and shoulder, particularly in middle aged males.It is often composed of relatively equal ratio of fat and spindle cells, yet either component may predominate.Because of its variable ratio, a spindle c